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Proviron (Mesterolone) 25mg/50tabs - Androviron | Innovagen

Brand: Innovagen

Trade Name: Proviron

Packing: 25mg/50tablets


Quick Overview

Manufacturer: Innovagen

Substance: Mesterolone

Pack: 25mg/50tablets


Chemical structure

Proviron is a modified form of dihydrotestosterone. Due to the addition of a methyl group at carbon 1, this drug differs from the dihydrotestosterone that protects hormone from metabolism in the liver while orally administered. In the orally taken tablets Primobolan (methenolone) the same structural modification is applied. Right after the first administration of the drug, the alkylation at the 1 position inhibits hepatic metabolism of steroids, although at a much less extent than at c-17 alpha alkylation. Mesterolone is an androgen, as well as dihydrotestosterone, and its anabolic activity is manifested at the low level.

Mesterolone is sufficiently resistant to decay, thus achieving a therapeutically useful level in the blood, even despite the fact that the drug has a much lower total bioavailability than 17 alpha alkylated steroids, which are used orally. Proviron has a fast period of recovery in the muscle tissue to inactive metabolites of diol, where concentration of the 3-hydroxysteroid dehydrogenase enzyme is quite high.

Do not think that the weak anabolic nature of this compound blocks androgen receptors in muscle tissue, thereby reducing the beneficial effects of other steroids that have a strong potential to build muscles. In fact, Proviron affects the activity of other steroids, turning most of them into free form due to its unique, almost identical affinity for plasma proteins, such as globulin that binds sex hormones.

Athletes use Proviron at the time of intensive preparation for a competition or during the course of a diet aimed at weight reduction to increase androgen levels and, due to its ability to bind to the aromatase enzyme, thereby not giving them the opportunity to convert testosterone into estradiol, serving as antiestrogen.

Historical reference

Proviron is one of the oldest androgenic anabolic steroids, one of the first drugs used in clinical practice for the treatment of hormonal disorders in men since 1934. Despite the fact that it was synthesized in the same years that testosterone propionate and methyltestosterone, it either could not be attributed to outdated drugs, since due to its efficacy and safety, it is still actively used in the clinical treatment.

In the case of mental and physical activity reduction, caused by natural aging, decreased libido appeared due to low levels of androgens, and for the treatment of gipogonadizm in  adolescents and aged men and infertility (the drug may increase the number and quality of sperm), it is recommended to use Proviron. However, the use of any androgenic anabolic steroids is a risk of infertility, and therefore the ability of the drug to give a positive result during the treatment is very contradictory. It is also known that many athletes take Proviron not correctly. When used in the recommended therapeutic dose, the drug does not significantly suppress the gonadotropins, and also does not affect the release of luteinizing hormone.

Proviron is recommended to use in addition to androgens, which are necessary for the sperm production. These androgens directly stimulate sperm production and affect the sperm maturation and transport, due to impact on the seminal vesicles, vas deferens, and appendage. This process shows us that such hormones can perform not only suppressive role. Due to the stimulation of sperm quality and quantity by Proviron which is not detected with suppression of gonadotropins, there are some cases when the medicament is used to treat male infertility.

Proviron has not received approval for sale in the United States, but because of its effectiveness and safety it is successfully sold in most countries, to be more precise, in more than thirty countries implement it in their territories. This drug can be found in the global pharmaceutical market under the names such as: Provi-Ron, Provironum, Mestoranum, Vistimon, Pluriviron and Restore. At the moment, the main supplier of Proviron is a Schering company.


For females: It is not recommended to use the drug by females because of its high androgenic effect.
For males: The recommended dosage for males constitutes 50 to 200 mg / day.
A Proviron cycle should not exceed 12 weeks.

Side effects

Proviron is referred to a class of androgenic steroids. During the use of androgenic steroids side effects appear quite often.

Side effects in men due to the testosterone use include alopecia, increasing hair growth on the body and face. Moreover, oily skin and acne may appear.

Side effects in females may occur in the form of increased growth of hair on the body and face, deepening of voice, periods’ irregularities, changes in skin texture and clitoral enlargement. Also, the enzyme 5-alpha reductase does not metabolize mesterolone, so administration of finasterine or dutasteride exerts no effect on its relative androgenicity.

Proviron does not cause any hepatotoxic side effects, due to the fact that it is not a C17 alpha alkaline compound, in other words the toxicity in the liver is very low. Steroids of such class negatively affect the cholesterol level in blood. This leads to a reduction of good cholesterol (HDL) levels and increase of bad cholesterol (LDL), which can lead to atherosclerosis.

The strength with which these steroids will affect serum lipids, depends directly on the dosage of the drug, the type of steroids, individual level of resistance to metabolism in the liver of specific organism and whether a drug is administered orally or by injection. Proviron does not aromatize and has no significant adverse effect on the lipids.

Clinical studies have shown that the use of Proviron in a dosage of 100 mg / day during six months in men with hypogonadism resulted in a significant increase of total cholesterol levels by 18%. Thus LDL cholesterol increased by 65%, and HDL cholesterol decreased by 35%. Also, studies have shown that, usage of Proviron in a dosage less than 150 mg per day, it has actually no influence on the level of testosterone, but if daily dose exceeds 300 mg, the drug begins to suppress testosterone greatly.

If you have cardiovascular risk factors, which exclude the use of certain steroids orally, so it is not recommended to take Proviron. It is better to minimize the consumption of simple carbohydrates, saturated fats and cholesterol, and regular exercises while carrying out a full course of anabolic / androgenic steroids in order to reduce the risk of cardiovascular strain. Also, a combination of a drug with natural cholesterol drugs and antioxidants, fish oil or products with comparable ingredients exerts positive effect.


Proviron is not recommended for use in case of hypersensitivity to the active compound of the drug, the detection of liver tumors, and prostate cancer.


substance Mesterolone


Customer Reviews

superb quality Review by CrazE
This proviron is the real deal. Sex drive is through the roof. Used for PCT as well. Great product all around. Thanks SC and Innovagen! (Posted on 12/22/2019)
awesome Review by bigTrev
I take proviron for the libido and it works for sure! 50mg a day is perfect. (Posted on 12/22/2019)

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