Innovagen Ermalone (Mestanolone) is an oral analog of dihydrotestosterone. This steroid is a methylated form of the powerful endogenous androgen, and it is the same for dihydrotestosterone that methyltestosterone is for testosterone.
Mestanolone is primarily androgenic drug. It has no estrogenic activity and has anti-estrogenic properties and it competes with aromatizing agents for binding to aromatase. This drug is desired by athletes due to its ability to give strength and aggression with minimal increase in body weight.
Dihydrotestosterone was synthesized in 1935. After that 17-alpha-methylated version also appeared. This steroid was not frequently used in clinical medicine. It was produced under the name of ermalon for short period of time. Most studies involving mestanolone were carried out in the 1950s and 1960s.
This was a period of steroids’ big bang. At first people thought that mestanolone possessed anabolic properties, but later it was found that it has androgenic properties. In the 1970s and 1980s it was used as part of the East German doping machine.
Mestanolone was evaluated not for its anabolic ability but for its androgenic essence. It improved the functioning of the CNS and neuromuscular interaction. Athletes claimed that it did not make them huge, but gave them speed, strength, aggression, stamina and resistance to stress. Mestanolone is still valued as an oral androgen.
Mestanolone – is a modified form of DHT. It is characterized by the addition of a methyl group in 17-alpha position that protects steroid when it is taken orally.
Estrogenic side effects:
Mestanolone does not aromatize and does not exert estrogenic activity. Anti-estrogens are not needed and even sensitive to the components people will not feel the symptoms of gynecomastia. Mestanolone is similar in chemical structure with dihydrotestosterone and also has anti-estrogenic properties, competes with aromatizing agents for binding to aromatase.
Androgenic side effects:
Mestanolone – is an androgen. Doses that exceed therapeutic ones may cause such androgenic side effects as oily skin, acne, hair growth on the body and face. It can strengthen the already existing baldness of male type. Women should remember about possible virilizing side effects. They may include deepening of the voice, irregular periods, change in skin texture, facial hair growth, and clitoral enlargement. Mestanolone does not react with 5a-reductase and its androgenity cannot be changed by use of finasteride or dutasteride.
Side Effects (Hepatotoxicity):
Mestanolone – is 17-alpha alkylated drug. This modification protects the drug from deactivation by the liver, allowing a large percentage of drugs enter the bloodstream after oral administration. Alkylated AAS can be hepatotoxic.
Using them for a long time or at high doses can lead to liver damage. In rare cases life-threatening dysfunction may develop. It is recommended to visit doctor during a cycle to monitor liver function. Intake of alkylated AAS is usually limited to 6-8 weeks in order to avoid increasing of the stress on the liver. It may be advisable to use the course supplements for liver, such as liver stabil, Liv-52 and Essentiale forte.
Side effects (cardiovascular system):
AAS can exert bad effect on blood cholesterol. This may be a decrease of good HDL cholesterol level, shifting of the balance towards the risk of atherosclerosis. Impact of AAS on lipids depends on the dose, form of administration, the steroid type and level of resistance to hepatic metabolism.
Mestanolone exerts strong effect on the cholesterol regulation by the liver due to its non-aromatizing structure, the structural resistance to break and the mode of administration. AAS can exert an adverse effect on blood pressure and triglycerides, reduce relaxation of endothelial blood vessels, cause ventricular hypertrophy that will increase the risk of cardiovascular disease and heart attack.
To reduce the stress on the cardiovascular system, it is recommended to minimize the consumption of saturated fat, cholesterol, and simple carbohydrates during the course of AAS. We recommend the use of additives such as fish oil, lipid Stabil or similar products.
Suppression of testosterone:
All AAS in doses that are needed to build muscle suppress endogenous testosterone production. Without the intervention of testosterone-stimulating substances, testosterone levels return to normal within 1-4 months after the cycle. Note that during the long period hypogonadotrophic hypogonadism can develop into secondary one and this may require medical intervention.
Administration (for men):
Effective dose to improve the physical form is in the range of 10-20mg per day during 6-8 weeks, to minimize the stress on the liver. At this level, mestanolone provides an essential increase in the power that is good for athletes of speed and power sports. With adequate diet, the androgen can reduce body fat and improve muscles by reducing water retention.
Reception (for women):
Mestanolone is not recommended for use by females due to its high androgenity.